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If you want to avoid UK capital gains tax by moving overseas it's usually necessary to remain non-resident for five complet

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e tax years. Any gains on assets disposed of after you leave the UK will then escape UK capital gains tax completely.

The

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ther side of the coin though is that you'll want to avoid or at least minimise any tax charges overseas. There's no point saving UK

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

tax at say 20% but then incurring tax overseas at 30%!

This is particularly the case when there are reliefs that will apply to redu

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

e any gain for UK tax purposes. The main reliefs that I'm thinking of here could include:

· A disposal of your home. The U

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

K provides for a full tax exemption on the disposal of your main residence (assuming it's been your main residence throughout your p

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

riod of ownership). Other countries aren't as generous and could only provide for a deferral (eg Spain which provides for a form of

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

rollover relief to defer the gain when you buy another main residence).

· Business assets. Examples here are properties th

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

t have been let to a trader. These could qualify for taper relief of 75%. This means that a higher rate taxpayer would have a CGT ch

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

arge of 10% - which is very low even by international standards

· Gambling winnings – tax free in the UK but not so elsewh

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

re

· Most debts are tax free in the UK – not so elsewhere

· Assets held long term. Any assets held for at least t

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

en years will in any case qualify for maximum non business asset taper relief. This will reduce the effective CGT charge for a highe

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

rate taxpayer to 24% and not 40%

Therefore this makes it very important to ensure that any overseas jurisdiction you choose offer

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

a CGT free or low CGT environment.

Low CGT jurisdictions

Italy 20%

Ireland 20%

Japan 20%

Croatia 25%

China

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

20%

Spain 18%

However when looking at these you need to bear in mind the opportunities above for low UK CGT rates.

CG

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

T free jurisdictions

If you want to avoid CGT in full there are plenty of these to choose from. Some of the most famous c

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

untries with no CGT or can offer a CGT free environment for expats with correct planning include:

Gibraltar

Malta

Andorra

Monaco

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

Isle of Man

Channel Islands

Cyprus

If you're thinking about moving overseas to avoid CGT you should ensure that you take detail

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

d advice. If you're interested in more articles on moving overseas and avoiding UK CGT visit elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ort.co.uk/" target="_blank"> http://www.wealthprotectionreport.co.uk for further details of offshore tax planning opportunities

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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