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I am taking the time to help others learn the basics in evaluating stocks for investment using both fundamental and technical analysis. Both tools are eq

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ually important in making serious decisions with your hard earned CASH!

If you wish to invest in stocks, treat it like a business, NOT A HOBBY. (ex: a r

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

etail outfit can't make money if it doesn't have goods to sell; the same goes for investors, without cash, you can't invest). You need rules and you need

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

to follow these rules or money WILL be LOST. Once proven rules have been established, they cannot be broke or you will lose money. Everyone loses mone

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

in investing but we must learn to cut losses quick and allow gains to develop. Small losses are acceptable because they teach us lessons that allow us

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

to win big!

Start your search by looking for stocks with superior fundamentals. After fundamentals are established, look to see if this particular stock

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

is in good company, by this I mean a strong industry group - similar stocks, historically move in the same direction (this is fact not opinion). This is

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

not to say every stock in the industry group will move higher or lower because a sister stock is going in that direction (this is a generalization rule).

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

After the industry group has been confirmed strong, determine if overall market is in a specific trend (up, down or sideways).

If you are long a stock,

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

the market must be in a confirmed up-trend, if you are short a stock, confirm a down trend. Note that 75% of all stocks will follow in the direction of

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

he overall market. Don't fight the trend, the market is always RIGHT.

Let the market and the stock dictate how long you will be in a position. Don't wo

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

rry about time frames; price and volume will tell you when to exit the position as long as you follow rules.

After fundamental have been established, yo

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

u must study the technical side of each individual stock, the specific industry group and the general market trends. Record if the stock is forming a pro

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

per base, if it's about to break out of a base, if it's extended or if it's pulling back to a key support line.

At this point, add any qualifying stock

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

o your watch list or buy the stock according to the technical entry signals (remember the fundamentals have been established earlier).

Key numbers

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

to use in fundamentals:
Earnings (current, past: quarterly, yearly and future estimates)
Sales (current, past: quarterly, yearly and

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

future estimates)
Return on Equity (ROE)
Price/Earnings Growth (PEG)
Price/Earnings Ratio (rise over time of base)
Debt/Equity

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ssets, Liabilities
Accumulation/Distribution ratio
Up/Down Volume over past several months
Number of Institutional Holders (is this incre

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

asing or decreasing recently)

Key things to use for technical analysis:
Look at the 1 year daily chart
The 1 year weekly chart

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

Check volume action when bases are formed
Look at Point & Figure charts for support and resistance lines
Look for new 52-week highs

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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In many sectors and industries recruiting good quality staff is a real challenge. Sadly, many organisations have more rigour around petty cash expenditure than one of their biggest investment decisions. So how can you stand out from the crowd?

Mezzanine loans are a particular type of commercial loans secured by an interest in the business entity that owns the property instead of an interest in the property itself. They have become a common alternative to convention subordinate loans.

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