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The value of the retail shopping property lies in the retailer’s ability to generate sufficient sales to pay ren

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

t and make a profit. Some retailers generate low sales per square foot of retail space but operate successfully

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

n very high profit margins. Others, such as food stores, operate on extremely low profit margins but have tremen

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ous turnover in merchandise, so the volume of sales makes up for the minimal profit margin. The retail shopping

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

enter is an important point of contact between both kind of retailer and the purchasing public. The retailer’s s

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

uccess determines the success of the shopping center, and the center’s ability to draw the proper mix of the buy

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ng public spells success or failure for the retailer. An analysis of retail sales facilities must focus on inf

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

rmation about shopping patterns, the economics of retailing, traffic flow, and retail design.

The term shopping

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

center is used here, as defined by the Urban Land Institute, to designate “a group of commercial establishments

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

planned, developed, owned, and managed as a unit related to location, size, and types of shops to the trade area

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

to which the unit serves.” Shopping centers are often classified by the market area they serve—region, community

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

or neighborhood. As a result of recent trends toward specialization in retailing, however, shopping centers may

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

also be classified by the type of shopping offered in the center. For example, specialty centers may offer high-

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

fashion or high-tech shopping, while discount or outlet centers offer continuous discounting in all stores.

A l

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

nder’s analysis of the shopping center operation and expenses often focuses on the design of the center and the

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ocation of tenants within the center. For successful operation of a shopping center, it is not enough simply to

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ill a center with tenants and offer their wares to the public. Leasing retail property requires knowledge of pro

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ducts, customers, and the relationship between them. If the retailers, architect, leasing agent, and developer c

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

operate closely, the retailers can gain the maximum possible exposure to the proper customer mix at the most rea

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

onable cost to the developer and at a reasonable operating expense for each. The rest is up to the buying public

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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