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Is the rehabilitation of America's addiction to foreign oil possible? Is it possible to

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

grow our own fuel and drill for our own oil? Carnations incredible thirst for oil, diese

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

l and gasoline is severely impacting our economic future. As gasoline prices hit four do

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

llars per gallon or five dollars per gallon during the height of hurricane season and oil

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

barrel prices reach $90 per barrel one has to wonder if the small businesses can survive

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

. We must break our addiction to foreign oil, but changing our factories to build altern

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ative fuel vehicles and switch from gasoline is no easy proposition. Many believe it is

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

impossible now for America to break the addiction to Middle Eastern oil.

The government

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

could provide tax incentives to promote flex fuels and biofuels, but many experts warn th

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

eir maximum capacity even if we go for it all the way by 2012 will only be 12 to 15% of o

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ur total usage and this may not be enough. What sorts of government tax incentives could

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

promote the use of flex fuels or biofuels? Well, what if we reduced the federal taxes on

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

gasoline by 7.5 cents per gallon if it contained 15% or more at all or 7.5 cents per gal

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

lon on bio diesel?

And what about the infrastructure? How can we get gas station owners

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

and truck stops to convert their pumps so that they can run bio diesel or ethanol blends

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

? Could we give the gas station owners a one-time tax credit of $40,000 to convert two o

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

r more pumps and their gas stations? What about the truckers and trucking companies? Co

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

uld we give them $2500 per year discount on their road truck taxes? We need to do someth

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ing and it needs to be a comprehensive plan, which gives incentives to car buyers, trucki

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ng companies, and fuel distribution companies alike. Perhaps you'll consider this a 2006

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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