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The technology that went into the Global Hawk unmanned aerial vehicle is

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

truly magnificent, but now the electronics and sensors have become much

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

smaller and therefore it is time to miniaturize the Global Hawk UAV.

I

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

t may be possible to build it at least one-third the size with the same

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

apabilities. That means longer-range, less fuel and it will be less like

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ly to be spotted. Why should the United States of America and the Unite

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

d States Air Force Research Laboratory go ahead and spend the money to m

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

iniaturize Global Hawk UAV?

It is simple really, less material to build

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

and electronic systems are now available and this means less cost, easie

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

r maintenance, more reliability and fewer downed units. It is time to m

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

iniaturize the Global Hawk UAV. When is the best time to do this? Right

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

now.

The United States Air Force and other military and quasi-military

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

agencies need more of these units right now and if we can make them chea

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

per and smaller that makes a whole lot more sense and additionally, we n

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ow have lighter materials and the smaller we build these things the stro

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

nger they will be.

Why use the Global Hawk UAV design? Because it seems

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

to work perfectly and a scaled-down version would work just as well. It

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

will still be a stable platform, with great maneuverability and it will

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

be a lot less weight. It is time that we consider miniaturizing this u

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

nit and increasing production tenfold. Please consider all this in 2006

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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