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He is brave who asks for forgiveness but the one who forgives is the bravest. It is not only difficult to forgive but at times it is difficult to forget. It takes a lot of c

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ourage to forgive and forget. In any form of relationships you or your partner or other family members are seen making mistakes and asking for forgiveness and then being exc

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

sed for faults and mistakes is a part of life. But at times your partner makes such mistakes that you find it difficult to forgive. Especially in a married life when one of

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

he partners hurts your feelings badly you find it hard to forgive. And even if you forgive you cannot forget it. It hovers over your mind and irritates you again and again.

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

o when you forgive learn to forget it too as unless you forget you cannot forgive completely. You are always suspecting your partner to be committing that mistake again. Tha

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

trust seems to have lost. In marriages couples often make mistakes. They involve into extra marital affairs, an act that is very common in relationships. Couples tend to ge

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

t carried away and involve into affairs with colleagues and other friends thus creating problems in their married life.

Once the secret is disclosed you or your partner who

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ever is on the wrong asks for forgiveness. You both sit together and forgive and start your relationship afresh. Everything is fine now. Your partner has promised never to r

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

peat that mistake again and as been forgiven by you. But actually everything is not fine. At the back of your mind you have questions filled up such as is he or she going ag

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

in with that person or with someone else? It’s quite late and your partner has not turned up you start thinking is your mate with that person at such and such place with suc

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

and such person who embittered your relationship. It is normal to have such thoughts. Although it is difficult yet it is important to learn to trust. Once both the partners

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

sit together to solve the problem and the offender comes up with a commitment never to make that blunder again then the defaulter should stick to his promises and never bre

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

k that trust while the offended should have full trust on the other partner. “Forgiving is the highest form of human behavior that can be shown to another person. Forgetting

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

is equally as high a human behavior; it is letting go of the need to seek revenge for past offenses.” You should show complete trust on your partner and should not constant

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

y ask him or her about questions related to it such as where have you been? Were you again with….! Such questions create an unhealthy atmosphere. There is distrust and it is

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

likely that your partner again commits the same fault, now out of irritation.

Loving and forgiving are the biggest asset in a relationship but that does not mean that the p

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

artner who has been pardoned need to repeat that mistake again. It is a heinous crime to break the trust again when once you have been forgiven. If you reiterate your mistak

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

after being pardoned then you need to think twice as what you do comes back to you. And somewhere or the other you would be paying for such mistrust. In the long run you wo

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ld be searching for a stable partner and find it difficult to get as a precious relationships are hard to find and even more difficult to find such forgiving and understandi

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

g partners.

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tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

Every salesperson and businessperson has had the experience of being close to closing a deal with a cooperative prospect, when suddenly all progress grinds to a halt. Any number of factors for the roadblock may be to blame. Maybe discussions hit a snag due to a miscommunication or a lack of understanding. Maybe one party allows their emotions to get involved in the negotiation process. Or maybe one of the parties has been dishonest about what they can and cannot deliver.

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