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Everyone says that they want their partners to always tell them the truth, but is that really the case

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

?

In my opinion, sentiments about always telling the truth in romantic relationships tend to be based

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

more on self-deception than reflective thought.

When it comes to telling the truth in a romantic rela

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

tionship, the truth cuts both ways. The truth can bring people closer together and it can push people

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

urther apart.

Telling the truth is important because it creates understanding, intimacy and closeness

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

But, telling the truth has its limits.

To begin with, couples don not always see eye-to-eye on ever

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

y issues that comes up. And discussing every difference is annoying and it causes unnecessary conflict

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

Sometimes pretending to get along is the wisest course of action.

Not only does withholding the trut

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

h sometimes help couples avoid unnecessary conflict, but the truth can also be quite harsh. Over the c

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

urse of a long-term relationship, partners are going to have negative thoughts and feelings about each

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

other. This is just a part of life. And sometimes it pays to keep one's negative feelings to oneself.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

The truth, once spoken, not only hurts, but it cannot be taken back. While negative feelings are often

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

fleeting, expressed negativity can last a lifetime. Unfortunately, partners are much more likely to re

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

member a negative comment than a compliment. When it comes to love and romance, some might argue that

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

t is better to censor one's thoughts before they are spoken.

And if people are so earnest about heari

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

g the truth, why do they punish others for being honest? Most people, when told an unpleasant truth, r

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

eact poorly - ranging from the silent treatment to a much more aggressive reaction. As a general rule,

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

such punishment is used to teach people the following lesson: Do not do that to me again. As you can s

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ee, a paradox quickly emerges. People say they want to know the truth, but their actions suggest other

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ise.

So, when a partner says "I always want to know the truth," that is most likely anything but true

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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