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"A man's got to do what a man's got to do. A woman must do what he can't." ~ Rhonda Hansome

"Behind every successful man is a surp

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

rised woman." ~ Maryon Pearson

"The most important thing that happened to women when they stood up for their rights was that they

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ost seats in the buses." ~ Anon

"Remember, Ginger Rogers did everything Fred Astaire did, but she did it backwards and in high hee

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ls."~ Faith Whittlesey

This power struggle is a turn off. I have heard it many times from different men. Why do we always want to

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

rove to men that we are smarter, tough, and independent? Why keep score? We are driving men away. We have already shown them that w

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

can, so now we need to back off. Many of us go to the extreme of putting men off in public, as if doing it in private was not bad

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

enough. We also tend to disagree with them whenever they say something.

Some men are usually not intimated by women who make more

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

oney and/or are more successful professionally; however, when face with this type of situation many men are losing their pride and

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

self-confidence.

The fact that women are being hired above men is an extra aggravation; after all, men like to be the providers an

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

protectors. This is their make-up. They have been doing this for thousands of years. When men lose their most fundamental role, th

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

n, what is left for them?

The fact is that men are not being taught to compete against women. Except for sports, which is consider

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

a given, men don’t know how to deal with this competition zeal. What is happening today is that we have created a society that is

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

oman friendly in detriment of men, who have come to be despised because of their masculinity. In other words, we are regarding men

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

as the enemy.

This is a tough situation. And since we already proved that we can do it, why not let it go? There is no need to kee

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

the competition going on forever. Enough, ladies!

A Word of Advice Ladies: If you find yourself in this situation where you have

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

become the provider, show more, and not less, affection. Be nice but not condescending; rearrange priorities so he can feel that he

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

is still the family’s bread-winner. For example, let him pay for the food and house, whereas you pay for nicer car, remodeling, va

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ations, etc.

Gents: Though it is easier said than done, try not to feel displaced. You indeed are very important. Take time off fo

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

r yourself and do what you love to do; perhaps start a new hobby or something that really makes you proud. And, in the words of W.C

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

Fields, "If at first you don’t succeed, try and try again. Then give up. No use to being a damned fool about it." Go have some fun

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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