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Live-in relationships maybe in the news these days thanks to recent movies but, there are still many questions about it. Are people actually living-in? What about the

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

societal and parental pressures? What if it doesn't workout? Here is what we find out...

COUPLE SPEAK

Finding out about your partner, before making the final commi

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ment, is often the reason behind this relationship. As BPO executive Mary Johnson, who is in a live-in relationship for the past six months, remarks, "I have very err

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

tic working hours so I want to check out if my boyfriend can adjust with me or not." On the other hand, DU student Anita Larson says, "I am very finicky about cleanli

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ess and other daily chores, so I have to be very sure about the guy I marry. I don't want these things to create problems in my life." Political Science student Ina B

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

iss and management student Glenn Dicks have taken an apartment together in New York city. "Right now, neither of us are ready for marriage. But, we are so much in lov

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

with each other, that we thought why shouldn't we live together?" justifies Glenn.

Among the professionals, the MNC work culture with long working hours provides th

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e rationale for couples opting for living together. Shruti Sinha, who works in a call centre, feels that she is open to both live-in and marriage and that her parents

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

have no objection to it. "But, in case I go for a live-in, I would definitely want it to materialise into marriage someday", says Shruti. Management student Marry Rie

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

er feels that it is always better to test the compatibility levels before you enter marriage. "Society attaches so much stigma to the divorced, plus it is a messy thi

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

g to happen. With live-in relationships it can be always be avoided," she says.

LEGAL SPEAK

Lawyers attribute the increase in live-in relationships among the young

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ouples to lack of patience and the inability to adjust to each other. "Everybody has a pre-conceived notion about marriage and now-a-days the couple wants to walk out

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

of it if it doesn't work out the way they had imagined. Due to the financial independence of both partners, none of them are willing to compromise," says Leslie.

"In

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

bility to be accountable for something reflects the immaturity of the couple these days. Earlier, in our parents' generation, the couples put up with each other. Toda

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

y, the tolerance levels have gone down," adds Donna Johnson.

APPROVED OR NOT

In most cases, the parents of the couple are not told about it. That is because, though

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

such relations are acceptable to the youth, it is still far from being accepted among the older generation, which continues to believe in the institution of marriage.

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

Remarks marketing executive Donald Saunders, "My parents have no clue about this relationship because they will never accept it. I will tell them about us only when I

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

am ready to marry my girlfriend."

The morality question about such arrangements bring about varied views. According to management student Jim Peterson, "If it is jus

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

to rebel against the traditional norms, it is useless and if it is to test a relationship, I don't think it is an appropriate way to do so." Rajkotia, however, refra

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ns from labelling it as either good or bad. "It's just an integral part of the new generation where the young want to make their own rules and defy traditional norms"

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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