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Q: What do you do with people who require blessings every day?

A: You keep blessing them everyday.

Do you have people in your life who truly bot

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

her you in big ways? I call them our soul attachments. Some people come into our lives for many reasons and a few are certainly intended to make u

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

pay some debts to our karma bank or to our thought patterns. They feel and look like those bugs that you want to get rid of but never succeed.

T

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

hey grasp your hair, crawl all over you, tickle and bite you leaving your skin itching, inflamed, and sore.

They get inside your ears making a pe

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

manent buzzing sound.

They get into your eyes making everything look blurred and teary.

They get into your mouth making things taste sour.

They

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

attach to your feet and give your blisters.

They walk all over you when you sleep, and then you have nightmares.

Having one of these people in

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ur lives is a terrible thing and much worse is having more than one. Some of us do. Sometimes, you haven’t seen these people for ages and sometime

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

s these people are not even living any longer. Still the sour memory of them is enough to trigger a huge discomfort in your being.

Having to live

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

with these people or their memory day in and day out, hour after hour, minute after minute is no picnic. It requires a massive dose of self-contro

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

l, determination, and forgiveness.

Not that they are constantly in your face, but the simple thought of them makes you wish you had a magic wand

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

nd then, with a flip of your wrist you could point it to the person and exclaim: "disapparatus!" or something like this and they would vanish.

Or

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

perhaps you wish you had you own pair of the ruby slippers and just by clicking the heels your wish would come true. Ah! What a great dream.

How

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ver, based on your history with this person or persons, this dream remains a dream, unless...

Unless you truly believe you have a magic wand or t

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

he ruby slippers, then the sky is the limit. Truth be told, we do have the wand and the slippers.

Though we can’t see them with our naked eyes, t

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ey already exist in all of us. We can do wonders with them; we only need to put them to work. They are called "thoughts."

Now, based on the Law o

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

f Attraction, you already know what to do with your thoughts: treat them with the utmost love, consideration, and respect; as though you are carin

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

for your silver vases. You clean, you shine, you protect, and you display them in the best part of your home.

So just do the same with your thou

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ghts: think positive; send love, bless; forgive. How long do you have to do this regarding those persons who really, truly bug you? Good question.

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

My answer is: How long is your life? You keep doing it over and over and over and one day, just like that, you finally understand with your heart

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

and you truly believe you have the magic wand or the ruby slippers.

That will be the day when they will go away from your life, once and for all

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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