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Perhaps you prefer the morning kiss before breakfast or the evening kiss as you enter home exhausted from yet another day of managing to do almost all you

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

had set before falling asleep the day before. Regardless of which type of kiss you prefer, experts agree that kissing is a great stimulant not only for t

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

he body but also for your brain.

How about mentioning some facts? First of all kissing is a great cardiovascular activity apart from an excellent process

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

to decrease high blood pressure and lower cholesterol. Due to the extra saliva production that a kiss initiates, kissing is a perfect prevention mechanism

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

against cavities and plaque, while it also prevents gingivitis due to the calcium that saliva contains. Thus, if you want to keep your smile looking just

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

perfect, do not forget to kiss often. Moreover, since saliva contains bacteria, which are 20 percent unique to each individual, kissing is a method of va

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

cination from new germs. As your immune system creates certain anti-bodies to these new bacteria you receive from your partner-also known as cross-immunot

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

herapy-your organism is able to vaccinate itself against the germs that enter your mouth while kissing.

For those of you that watch your diet, keep in mi

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

nd that a kiss burns in average 12 calories per five-seconds and that three passionate kisses a day can help you get rid of a whole pound in a month! In a

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

dition, since kissing puts to work over 30 muscles of your face, your skin becomes smoother and due to the increase in blood circulation its tone and colo

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

r become more even and you look healthy and beautiful.

Before getting your partners lips close to yours, have you ever thought why you are kissing that s

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

pecific individual? Well, we know you love him or her, but did you know that a part of the kissing process actually helps your brain perform some chemical

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

analysis of your partner's saliva and "decides" on your genetic compatibility? Researchers after examining a number of cases have concluded that a kiss ca

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

n be actually apart from fun the "verdict" of your brain to your choice of a partner. Isn't that a sweet deal?

Your remember of course phrases like "kiss

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

and make-up" or "kiss and make it all better" and sometimes you probably have even laughed at the idea that a kiss can make your relationship better or l

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

t a problem vanish to thin air. Well, although it is difficult to believe this is true, kissing helps your body produce the "happy" kind hormones-called e

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ndorphins-which are actually your natural body's tranquilizers and help you regain control over a stressful situation.

Whether you kiss your partner upon

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

remembering your favorite movie scene, or just because you want to make your hiccups stop, kissing is always a good excuse to come closer with that speci

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

l one and remember all the things that make you happy when you are together. Our advice is that every hour of every day is a good excuse to kiss and feel

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

happy and alive! Many believe that kissing most of the times can be so much more than words. Kiss and let your actions speak louder than your loving voice

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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