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"It is the way we react to circumstances that determines our feelings."

-Dale Carnegie

When we think about talking about our feel

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ings or being emotional, generally we think of women. Psychologists have discovered that men clearly deal with their emotions dif

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ferently than women. Men Are From Mars Women Are From Venus, by by John Gray speaks to the many differences in the genders.

It'

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

s almost as if we brush men's feelings under the rug because we know they will handle it on their own and bounce back. But, we c

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ome running to the aid of our girlfriends because they "need" us. Let's face it, it's a whole lot easier for awoman to cry on

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

our shoulder than it is for a man.

Women come with a built in support system. If they're heart broken they simply call a friend a

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

nd get to cry their hearts out. If a guy is hurting over someone and calls a friend; more than likely there won't be a whole lot

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

of crying going on.

They may hear stuff like: Sarah who? She wasn't worth it anyway. Or, forget that b*tch and let's go out. Or,

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

come on man, feel bad for 5 minutes and get over it, the games on tonight.

Feelings aren't something that men share with their b

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

uddies. Unless they have friends that are women they will have to deal with all of their emotions; alone. Even though it's more

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

accepted for men to talk about their feelings now, they typically aren't consoled the same way a women would be.

But, the realit

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

y is; that it is just as painful for men to go through a breakup or divorce as it is for a women. We may have are many differenc

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

es, but a broken heart feels the same whether it's in a man's body or a woman's.

So for all of you men out there who are quietly

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

suffering through your heartache, it's time to reach out and touch someone. Don't be afraid to talk to your "girl" friends, you

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

'll never find anyone more understanding. Find your way to a "relationship forum" on the internet. There you can anonymously pou

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

r your heart out and get some pretty good advice.

Go to the book store and read something that soothes your soul. Hang out with

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ood friends. Keeping yourself busy is key to letting go of the past and moving forward. We all know it's no fun to have to go th

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

rough, but the sooner you deal with your feelings and let them go; the better you will begin to feel.

Things don't always work ou

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

t the way we want. But, as you know, it's not what happens to us that matters as much as how we handle it and who we become afte

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

r we've lived through it. Just like we tell our girlfriends, "Don't worry, you'll get over it." They always do and you will too

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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