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Intimacy is a combination of four aspects of a person; the physical, emotional, intellect

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ual, and the spiritual. Most relationships will fall into one or two of these intimate as

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

pects.

Physical Intimacy

Physical intimacy s the easiest one

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

o be involved in, it usually begins with a handshake or a hug. In general the more attrac

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ted you are to someone the more touching that will occur.

Emotional Intimacy

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

We tend to guard ourselves from getting emotionally attached to people to

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

quickly therefore it usually takes more time to develop emotional intimacy with someone.

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

This is when we begin to share our opinions, feelings, fears, and dreams.

I

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ntellectual Intimacy

Just like emotional intimacy, it takes longer to esta

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

lish than physical intimacy. However, it does so because intellectual intimacy requires a

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

number of different experiences. Conversations based on different types of cultural and

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

political events that allow you to reveal your own personal philosophy of life; is the mo

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

t common way to create intellectual intimacy.

Spiritual Intimacy
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
g>

Spiritual intimacy is the rarest and most challenging form of intimacy. Spiritual int
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
imacy has little to do with religious beliefs as couples with identical and different rel
t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
gious beliefs can achieve spiritual intimacy.

Spiritual intimacy is a respect for each o
ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust
ther that turns into each person doing everything in their power to make the other person
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
the best version of him/herself.

To understand intimacy we must move beyond physical in
.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
imacy and begin to know all four aspects of intimacy.

To know someone in all four or eve
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip
n in more than one intimate level makes each level of intimate knowledge that much better

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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