Suggest - Relationships

Wait a minute:

How come it's okay to fight to get to the top of your class but not okay to fight with your best friend or confidant to get to the best outcome regarding a di

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

fference of opinion you two have over something you both care about? Just as there are "fair" ways to fight with cancer (i.e. chemo therapy rather than a shot gun), there ar

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

fair ways to fight with your spouse or boss.

Friends, siblings, business partners, lovers and mates need to learn the art and skill of fair fighting. If you don’t, you’ll

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

fight unfairly and that is destructive. If you don’t fight, you’ll miss the healthy benefits of fighting.

It is human to have conflict. It is okay when we hear of a person

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ho fought and struggled or strived to get to the top of their field of endeavor. We cheer for the person who has won their fight with cancer. We don’t so much like to root

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

or the friend who argues with or contends with another friend of ours. Kids don’t applaud their parents when fighting. Mothers, unlike football coaches, don’t video tape t

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

eir children’s quarrels with each other and afterwards give them pointers as to how they could do better arguing. What’s going on here?

So long as we follow the rules of th

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

game, it’s good to have a competitive, heated tennis match with an vopponent. The same holds true for an emotional match with our spouse. It toughens us, makes us better i

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

that arena, and teaches us a great deal about the other person and how they function. Fighters know each other about as well, perhaps better, than passionate lovers.

Relat

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

onship conflict helps to keep up boundaries. With healthy boundaries we are better able to co-exist with another person and not be threatened or insecure. Basically when we

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

speak of a person winning a struggle with cancer, what has happened is not the elimination of cancer cells from their body. Rather, the cancer has been put in its place, bac

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

into a low level of prevalence to keep the body balanced and healthy. We all have some cancer cells in us at all times. Healthy struggle with cancer cells keeps them from

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

rowing too fast and taking over parts of the body.

Fair fighting in relationships ventilates grievances so resentment stays down, increases coping abilities and keeps power

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ifferentials at manageable levels so that the relationship stays balanced. Done right, conflict can solve problems and fix disorder.

Here are basic rules for fair fighting:

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

1. No physical violence or emotional abuse while talking/fighting.
2. No name calling or cussing out the other person.
3. Stick to the topic of contention. No

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

bringing up the past, unless that’s the topic.
4. Avoid lying and exaggerating as in “You always......” or “You never......” or “I’m the only one who ever......”. State

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ents such as these are useless untruths and do little to enhance problem solving.
5. No walking or running out of the fight. If you need a break because you’re getting

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

oo emotional to think clearly and remember the fair rules of fighting, ask for a break and agree when the fight will resume. You do not have to say this relationship is over

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

or ask for a divorce just to take a time-out.
6. No ultimatums or threats. The point of fair fighting is not to win but to struggle with your partner until you can come

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

to win/win solutions or compromises. In the meantime enjoy sparing with the other person and sharpening both of your abilities to stay afloat in the world of human realities

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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