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    John saw Jenny and they happily lived ever after!’ Goose stories, told by nannies to their grand daughters who are going on their firs
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    t date. The grand daughters of today want an articulate, suave and interesting guy to begin with. The foremost trait this grand daugh
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    er is looking for: ‘Can this guy converse?’ The first complete sentence John is going to utter might end the John-Jenny story right he
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    re!

    Tons of paper and GBs worth of virtual space has been spent on deciding the one articulate, interesting and suave combination of
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    ords which will eventually lead John to woo Jenny. To be frank, I am of the opinion that there is no ‘Men are from Mars, Women are fro
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    m Venus’ type answer to this query. No amount of man-women analysis has been able to give us fair and square answer to this question.
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    Suggestions range from a nice and decent Hellos, to a curt and challenging introduction. What they all boil down to are the absolute b
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    asics that a guy has to adhere to and get a maximum out of the situation at hand. Illustrated below are a few of the essential princip
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    es that a guy must stick to start and sustain the conversation :

    (a) Get your body language straight; Be confident, upright and speak
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    your sense. Don’t use submissive, apologetic body language and voice tones. A lot of initial conversations die a premature death if t
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    e guy pleads to begin one. What we forget is that a woman is picturing things as we speak. Wherever you are and whatever the situation
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    , you must remember that your composure and body language are the key.

    (b) Mentally prepare the approach to the woman. Meeting are de
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    tined in heaven, but to ensure that it reaches the gates of heaven ( pun intended) together is up to the people involved in them. Don
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    ’t just march to a lady and start babblings. Prepare the approach and you will be happy in the long run. However, I must add, ‘Don’t m
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    ke it too complicated’.

    (c) Don’t try and get a forced response from her. A woman is attracted to a man who is a challenge to her. M
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    ake this challenge achievable is u want to dominate a relationship. Maintain the alpha-status and she will be glued to you. Say what c
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    mes to your mind (and heart) seeing the situation. Start off with a small hello and continue with a leading question.

    Finally, rememb
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    er it’s a conversation; both have to share the mantle. Be prepared to guide the conversation to a mutually convenient topic. This impl
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    es that you have to start with the initial question and look beyond. Start with the aim to keep the conversation going; that will ensu
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    re that you progress in the relationship and maybe start the journey granny told you about – the one which lead to the gates of heaven


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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