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Just saying sorry when you have done something wrong or hurt another person’s feelings is not enough to rectify th

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e hurt you might have caused. When we are arguing or trying desperately to prove our point, we sometimes unintenti

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

onally hurt the person who is listening to us. As soon as we realize our mistake, we immediately say sorry and thi

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

nk that our duty has been fulfilled. We want things to be as normal as they were before. But that is not possible

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

f we’re not genuinely sorry. You say you’re sorry just to keep the relationship on track. If you don’t mean it cha

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

nces are the other person is never going to forgive you.

Often people keep grudges in their hearts against other

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

people just because of small matters. If you don’t clarify things on the spot they might come back at some point l

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ater in your life and turn out to be some occasions where you made a mistake and did not resolve it properly befor

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

moving on.

Whenever you apologize make sure you mean it. Don’t bring in third parties to talk to the person you

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

have offended. Always handle your personal matters yourself, especially if the person you have hurt is your lover

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

or a dear friend. If you think saying sorry in person is not going to be that much effective, then write a letter,

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

buy a card or simply email your friend and tell them your true feelings without hesitation. Tell them that you wi

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

l never make such a mistake again.

Also make sure that the time you have selected to apologize is the right time.

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

If the person you have hurt is not in a position to listen to you then don’t press them. Give them sometime to th

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ink and then send an apology note. Accept the fact that you were wrong when you hurt their feelings and promise th

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

at you are going to be extremely careful in future.

A genuine apology is the one that sets things straight betwee

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

two people and neither of them keeps a grudge. If you think that you were right then wait for a little while befo

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

re realizing your next action. Think again about your argument. You do owe an apology to a person if you used hars

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

h words or said something you shouldn’t have said. But before saying that you’re sorry make up your mind and then

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

honestly tell the other person that what happened was not right and that you two should try to set things straight

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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