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    Now this is a tough one and practically depends on what situation you are in. There can be three scenarios one is when the guy is genuinely in need of some mon
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    ey and you are the only one who can lend it to him at this point in time.

    Second is that the guy is simply in the habit of indulging himself and cannot keep a
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    check on his expenses and ends up over stretching himself always. In such a case it is more likely than not that he is simply taking advantage of your kindnes
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    s. The third case is somewhere in between the guy is basically good but sometimes he gets into stuff that lead him to a situation where he needs more cash tha
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    he has and so every couple of months or so he has to come to you for some money.

    And another thing which is important is whether you get repaid at all or not
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    . If you get repaid then there is no cause for worry you are probably just helping him through some cash flow problems. However you must keep in mind that the
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    amount that he asks for should not keep increasing over time which only signs at situation where suddenly he takes a lot of money and then is not in a position
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    to repay it.

    Another good way for girlfriends to judge how to deal with the situation is to get a grip on where the money is going and then act accordingly. I
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    f the money is going on indulgences then you should stop lending to your boyfriend immediately. These can be in any form and not necessarily what we see as vic
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    es like alcohol or gambling. For instance if your boyfriend has a penchant for expensive clothes which he cannot afford and still takes money from you to spend
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    on them it’s a vice that he can and should live without and you should not pamper him in ways that are detriment to both of you.

    If you have decided that it i
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    s a case of indulgence and unjustified spending you should take a strong stance against this and say “no”, no matter how uncomfortable it becomes.

    It’s diffic
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    ult for most of us to say no and it becomes especially difficult in situations such as these when two people are intimate and spend a lot of time together. But
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    it’s important to say no because maybe you are heading for a potentially disastrous situation one you definitely do not want to enter and may be even deserve.
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    Money problems are one of the worse that any couple can hope for and they may even lead to separation. But think over it if all a guy needs you for is money th
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    en its probably better to just snap out of it. However it is equally important to recognize that there are a lot of chances of miscommunication and its best to
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    bring it all out in the open. You should take a stance depending on your situation which would either be no more lending at all or controlled lending and be r
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    ady before hand for some uncomfortable questions and situations that will arise when you are going to make this conversation. If you think through it you will
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    be able to come out with reasons on why this is the best for both of you and how you think it needs to be tackled now itself and not later.

    Relate all this to
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    your boyfriend in a calm manner and hopefully he would understand but if he does not you have to take a tough decision and decide whether he still is worth it


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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