Suggest - Relationships

Are you unhappy with your relationship? Are you confused with the way it is and can’t understand how it got so bad? Are you looking at how to find a solution

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

to what seems like an unsolvable problem?

Intolerable situations are parts of your life and relationship you have been putting up with that are wearing you o

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ut, both emotionally and physically.

If you find yourself dealing with issues in which you feel stuck and can't seem to find an answer to, consider the follow

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ing questions:

*What were your top five needs at the time you got in the place you are in?

*Were you frightened, so you settled for where you are out of d

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

esperation?

*Did you think you didn’t really have any other choices?

*Have you currently outgrown those needs?

*Or do you need to find better coping strateg

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ies if you must stay where you are?

Think about the following ideas to help you resolve your situation:

1. Perceived needs aren’t necessarily the tr

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

uth.

Every time we have an intolerable situation, it is because we had a perceived need or value that has become too expensive in our lives. For example

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

, you may have had a need to marry someone who could take care of you economically. However, after living with this person, you may find that the cost has bee

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

n too high to your mental and emotional health, and that in fact, it would be easier to learn how to take care of yourself.

2. Some commitments are costly

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

.

Sometimes we have an unrealistic commitment to a value, which causes life to be difficult. For example, you feel you must be loyal to a friend, or a r

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

elationship, no matter what they do or say to you. You may be so committed to the value of being loyal, you have forgotten how to be kind to yourself.

3.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

Picture the future.

How long can your intolerable situation continue in your life? Can you picture what your life will be in 2007 if you continue being

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

where you are? How about 2006? Sometimes picturing the future helps us let go of what is intolerable in the present.

4. Discover your choices.

Whe

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

n we are in intolerable situations, it is difficult to access our creativity to generate what we need. What are your methods and patterns for coping with stre

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ss? Can you consider a different strategy to deal with this situation? We always have choices.

5. Take one action; change one thing.

Go back and l

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ook at your life in the past. When was it as bad as it is now? How did you deal with the stress then? What one thing could you change that you did not do in

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

the past that would have made your situation easier?

False, unrealistic hope can make all of us gullible. Many people commit to a relationship because they h

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ave an illusion of what they want, rather than being able to see what truly exists.

After you make a list of all the possible choices you have, and the action

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

s you can take, make a list of people you can talk to about them. Ask for insight into your patterns, history, and reactions to stress.

Once you get yourself

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

unstuck, you can look right around the corner for the one who looks for you. Because you will become more available and more alive with your own possibility.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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