Suggest - Relationships

There are many factors that go into creating a loving relationship. Certainly it helps if two people have some things in common regarding how they like to spend their time. It also helps if the

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

y have common values around religion or spirituality, around politics, the environment, abortion, and personal growth. It helps if they both eat junk food or both eat organic food. It makes t

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

hings easier if both are neat or both are messy, if both are on time people or both are late people. Physical attraction is also quite important. It’s great if they have common values around

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

money and spending.

Yet a couple can have all of these and still not have a loving relationship if one element is missing. Without this essential ingredient, all the other wonderful attributes

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

will not be enough to make the relationship work.

This essential ingredient is about intention.

At any given moment, each of us is devoted to only one of two different intentions: to control o

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

to learn. When our intention is to control, our deepest motivation is to have control over getting love, avoiding pain, and feeling safe. When our intention is to learn, our deepest motivation

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

is to learn about being loving to ourselves and others.

The motivation to get love rather than be loving can create havoc within a relationship.

Let’s look at a typical relationship issue an

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

d see what happens regarding the two different intentions. Jason and Samantha are feeling emotionally distant from each other, and they haven’t made love in a month. The problem started when

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

Samantha stated that she wanted to take an expensive vacation and Jason objected. Samantha got angry, Jason gave in, and they have been distant ever since.

Samantha’s intention was to have con

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

trol over getting what she wanted. She equates an expensive vacation with love – if Jason does this for her, then he proves his love for her. She used her anger as a way to have control over

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

etting what she wants. She wants control over feeling special to Jason.

Jason’s intention is to avoid pain. He gave himself up to have control over Samantha not being angry with him. He hopes

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

that by giving Samantha what she wants, she will see him as a good and loving husband.

However, because both Jason and Samantha were trying to control each other rather than be loving to th

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

emselves and each other, their interaction created emotional distance.

What would this have looked like if their intention had been to learn?

If Samantha’s intent had been to learn, she would n

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ot have become angry. Instead, she would have wanted to understand Jason’s objections. If Jason’s intention had been to learn, he would not have given himself up. Instead he would have wanted

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

to understand why this particular vacation was so important to Samantha. Both Samantha and Jason would have been caring about themselves and each other, rather than wanting to get love or av

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

id pain. In their mutual exploration about why they each felt the way they did, they would have learned what they needed to learn - about themselves and each other - to reach a win-win resolu

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

tion. Instead of Samantha ostensibly winning and Jason losing, they would have come up with something both of them could live with. With some exploration of his financial fears, Jason might hav

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e decided that the vacation Samantha wanted would be fine. With understand of Jason’s financial concerns, Samantha might have decided on a less expensive vacation. In either case, both of the

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

m would have felt fine about the outcome.

No matter how much Jason and Samantha have in common or are attracted to each other, their love will diminish when their intent is to control rather

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

than learn. It’s amazing how quickly love vanishes when one or both partners have the intent to control. It’s equally amazing how fast it comes back when both partners have the intent to learn

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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