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    Have you noticed? The farther people live from each other, the more opposite the traditions become. It is obvious that it is concerned with culture and with climate zone and with the composition of the population (for instance, in multi-national
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    countries people are more tolerant to the customs and traditions of others and sometimes traditions get mixed and intertwined).

    Nevertheless, the people of different nations long for each other! People abroad are looking for something that the
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    r society has lost. It turns out that the difference attracts people, but at the same time it causes conflicts.

    A simple example. One of our couples is waiting for a fianc?e visa, the groom writes in the letter to his bride that when she comes
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    to America, she will find the full wardrobe of clothes for herself which used to be his sister’s. She died from cancer at the young age, that’s why all her clothes are modern and in good state. I don’t know if it is really common to wear the clo
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    hes that belonged to the deceased? Tell me about it! Because recently the stories like this happen quite often: some men even bring things of the deceased as a gift, as a souvenir, as a keepsake. Judging by this I can conclude that American peop
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    le think that’s ok. However, it will shock any Russian!!! Most Russians won’t put on things of the dead. For centuries people made up horror stories about those who took the things of the dead! Folk tales are ruthless: those people either die or
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    give everything back and repent :)

    This is taboo that stays deeply in mind. Now imagine yourself in the shoes of this girl: to refuse means to hurt the memory of his sister, but at the same time she won’t be able to wear these clothes. Add to t
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    his the hard adaptation period in a new country without relatives and friends. What will she feel?

    Certainly, there are exceptions. There are people without any superstitions; there are very poor people who are glad to any clothes. Everything I
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    write about in newsletters is only a general tendency, all people are different. But it is necessary to know about these things if you want to have a Russian wife.

    The exception is family relics and jewelry. They are passed on from generation t
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    o generation. But people don’t wear these things every day, just keep them and from time to time blow dust off them. :)

    Here is one more example of completely different traditions. It is a custom in Russia to give odd number of flowers. Very of
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    en our clients order, for example 10 roses and we have to explain each time that odd number of flowers is given only to the dead. There was an incident when a Russian girl slapped a foreign man in the face with the bouquet of 4 roses!!!

    Well, a
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    nd the last example. (It is possible to give a lot of them, but it is not the purpose of the article). Russian married people wear a wedding (engagement) ring on the right hand, divorced – shift it on the left one. How is it in your country? Sup
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    ose, the other way round?

    The collision of traditions and mentalities is inevitable in international marriages! You shouldn’t be afraid of it, you should simply be ready. If there is love in your family, it will only enrich your spirit. You wil
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    l find what you missed in your environment: new outlook, renewed life, family values. But how to achieve it and to overcome the first barriers of misunderstanding?

    The advice is simple:

    1. Communicate more with Russian people, learn their cult
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    re, take interest in customs. Be active: spend Christmas in Russia, take part in Russian wedding, accept the invitation to the birthday party of your lady’s friend, visit Russian church. At that, soak up the information like a sponge.

    2. Try to
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    read the books of the Russian authors. I know many clients who started looking for a wife among Russian girls after they had read Russian authors. I understand that it sounds impracticable! :)) Ha-ha-ha! But it is one of the right ways!

    3. If
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    ou came to a difficult situation with your bride or a wife, don’t rush to make conclusions! Possibly, it is just the situation when your outlooks on life didn’t agree! Your actions: talk about it with someone from Russia. Or you can ask for help
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    at the Husbands of Russian Wives’ Community. I’ve met these kinds of associations in the Internet. And make sure to explain the cause of your each action. It seems obvious to you, but not to your wife! Imagine that you are communicating with Mo
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    gli who was brought up in the jungles. The comparison is possibly insulting for women, but it is to the point. Instead of jungles there is another country, and instead of animals – the people of a different nationality, possibly less familiar, l
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    ess studied than some kinds of animals!

    4. Be patient!

    And always remember that you view the world from different ends of the ocean!

    If you faced the situations like these, it will be interesting for all of us to learn about it. Share with us


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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