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In a long term love relationship, you are either drifting apart or getting closer. Y

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ou really do not get to stand still.

Here are 7 tips for how to get closer and make

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

your relationship better and better.

1. Make a list of "little things" you know

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

our partner likes and enjoys - Keep it with you, in your wallet, purse, briefcas

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

or bathroom mirror to remind you.

2. Ask your partner "What can I do today,

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

this week, month, year, lifetime, that will help you feel loved by me?" Once you fin

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

out the answers to these questions, my suggestion is to take the radical step of do

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ing them.

3. Catch your partner doing something you appreciate - Then tell t

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

em. Every single one of us likes to be appreciated. Being appreciated is a great way

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

to draw one close.

4. With your partner fill in the blanks for the following

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

statement:

"I feel closest to you when.............."

This is another working list

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

to help keep your income on track.

5. Think back over the history of your relati

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

nship - What were the things you did that brought the biggest smile to your part

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

er's face? What touched their heart the most?

Then, if at all possible, do these th

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ings again!

6. Ask your partner "What would a perfect day look like for you?

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

And then create together as much of that perfect day as you can.

7. Consider to

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ether the times you have felt the closest. This is so simple yet so profound. Ma

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e a list of the things you were doing that contributed to the feeling of closeness,

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

nd take the time to do them again.

Good strong lasting relationships don't just hap

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

en - they are created by putting hands and feet on love and acting and living it out

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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