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There are two layers to life, work and love. One is above the surface and one is below. Above the surface is how you look, how you feel, how you act, how you manifest your life in hard goods and tangible reality. It i

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

s important.

Below the surface there is another world. It is a world of sensations, emotions, moods and connections. No one sees this world. Your “above the surface” world is all people see. To detect what is below t

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

e surface, we must use our intuition. This intuition is possessed by everyone but understood by few, and trusted by even fewer.

The world above causes the world below. Many people confuse this. The spiritual seeker m

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ght say that if I meditate, I will achieve a good life. But this is false reality. If we live a good life, we will meditate. The above causes the below. “As above, So below”

The keys that cause our world above to suc

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ceed are the diametrically opposite rules to the ones that cause success below. The ego – drive, attachment, pride, lust, ambition, emotion give us victory above the surface while detachment, love, compassion and cont

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ntment (not wanting or desiring) create victory below. A fulfilled ego, often gives the space in life for the experience below the surface to be witnessed.

One woman came to me for a consult. She was meditating daily

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

in order to find the inner space of love and peace. She was having an affair behind her husbands back, so her mind and heart were very disturbed during the day. She was achieving nice peace in her meditation but not s

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

o nice during her day.

She was not wrong or bad, she was simply meditating for the wrong reason and on the wrong topic. Inner peace comes from good living and compassion not from meditation. No meditation can counter

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ct the disturbance that comes from self serving and conflicting values in everyday life. Meditation is different to this. It is, ultimately, about other, rather than self.

Meditation is simply a reminder. It reminds

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

s, that before we do all these things in the day, we are something special anyway. Meditation can knock some of the fear and anxiety out of our lives by reminding us that we are, even without all the surface attachmen

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

s and adornments, worthy of love. Meditation replaces our parents love, with universal love, when the time is right.

So, please be careful. The purpose of religious values is to give us some sense of outer peace, a m

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

oral code, a sense of alignment between what we do, and what we value. With such a life management process, the inner world comes to life. The two worlds one above the surface and one below, are really interconnected.

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

Loving acts of generosity, kindness and care lead to an outer harmony. Then the life below the surface can be opened. The role of meditation is to connect the two. There is nothing you need to do to improve the world

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

below the surface. It already exists in absolute perfection. This is the very definition and purpose of spirituality. To discover that perfection exists already.

The world above the surface, the ego and the material

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

experience of life, drives you to growth because it destroys the awareness of that perfection below the surface. We keep coming back to the world below, because the world above becomes disturbed. We loose touch with o

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

r inner peace, our inner harmony, not because we have not meditated enough, but because we have judged ourselves above the surface. Broken our own code of worthiness.

Finding true love comes from the inner world, tha

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

which exists below the surface. True love bypasses all the outer realms of our lives, sneaks in under the radar, and enters us. However, to sustain it, our outer world, above the surface, must be aligned.

Meditation

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

connects you to love. This is the ultimate end. But if your outer world is corrupted, thoughts are judgemental, ideas are stuck, emotions are out of control, stresses are not worked through, materials are not seen as

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

decorations then, love cannot survive. Finding true love requires the skill to become open and this is the key we so struggle to hold.

Open? The implication is perfect and beautiful. It means love is there, beneath t

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

e surface, crowded and clouded by the life we choose above the surface. To become open to love therefore means to arrange our outer world in such a way that it never, ever becomes a blockage? How?

With spirit and lov

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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