Suggest - Health and Fitness

What do we envision when we think of aging skin? Wrinkles, fine lines, crows feet, skin blemishes, liver spots, just to name a few. Basically, the proble

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

m is that when we age our skin starts to lose its elasticity and ability to repair and restore itself. When we injure our skin and get a bruise it may not

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

heal completely and leave a spot or similar blemish. When we stay out in the sun too long and develop sun spots, wrinkles and more they don’t quite compl

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

etely go away anymore. This is the result of aging. There are many factors that contribute to the aging process and there are now treatments that can hel

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

p and reverse some or even all of this damage.

Aging is a natural process and regardless what nutrition regimen you follow it will occur. Even the best n

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

utrition programs like Dr. Perricone and Dr. Obagi will only minimally slow down the aging process. This is where plastic surgery, steroids and hormone th

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

erapy, lasers, anti aging creams and medium depth skin peels like the TCA skin peel come in. Plastic surgery can make anyone look younger, but it is very

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

expensive and not an affordable option to most consumers.

There is hormone therapy, but this has mixed reviews and is also very expensive. It is importan

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

t to note that an increase in certain hormones can lead to undesirable effects like hair loss or thinning on the scalp, new facial hair growth, and serious

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

side effects like cancer and liver disease. Lasers and skin peels are slightly more affordable but still expensive at $200 up to $1000 per treatment and

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

many require several treatments to see good effects. Then there are the various anti aging skin creams we see hawked on TV and in almost every magazine.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

All promise great results, but after buying one you find it doesn’t really work that well if at all.

There is one tried and true anti-aging skin treatment

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

that is actually affordable and has been found effective for this use by the American Medical Association. It has also been successfully used in millions

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

of doctors offices throughout the world, the medium depth TCA skin peel. TCA stands for trichloroacetic acid. It is a facial peel, but is stronger and m

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ore effective than any other skin peel. The TCA peel has been featured on numerous TV shows like the Swan, Dr. 90210, and various reality shows for its ab

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ility to renew and rejuvenate the skin. It is important to note that in a doctors office the cost can be $200-$500 or more per peel, but TCA peels can now

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

be purchased for in home use for under $30 which makes them the most cost effective anti aging treatment currently available.

The latest medical research

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

has proven that TCA peels do work as a proven treatment for wrinkles, freckles, sun spots, blemishes, and other numerous conditions usually attributed to

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

the aging process. Plastic surgeon Dr. Keith Leiberman explains: "Unlike other techniques, TCA skin peels get to the root of the problem with aging skin,

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

resulting in tremendously effective results - leaving the patient with noticeably fresher, smoother skin and great texture...with fewer wrinkles and lines!

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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