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In many countries, steroids are legal and even can be purchased over the counter. As a results many of these injectable anabolics are administered by the

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

user. Below is information aiding in the conversion of such drugs. This article does not endorse the use of illegal drugs.

I. U.= international unit.

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

This is a unit used to measure the activity (that is, the effect) of many vitamins and drugs. For each substance to which this unit applies, there is an i

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ternational agreement specifying the biological effect expected with a dose of 1 IU. Other quantities of the substance are then expressed as multiples of

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

this standard. This also means that this measurment is not based on sheer volume or weight of the substance, but rather the effect.

ml = milliliter. This

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

is a VOLUME measurement. it is 1/1000 of a liter. when talking about water or similar liquids, it is equivelant to one cubic centimeter.

cc = cubic cent

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

meter. This is also a VOLUME measurement. Most syringes measure their capacity in cc's. If you have a 5cc syringe, it will hold ~5ml of liquid in it.

mg

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

= milligram. This is a WEIGHT measurement. It is 1/1000 of a gram. the amount of chemical substance is often measured in milligrams. For injectable soluti

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ons, this will be reported as a concentration of weight to volume, such as mg/ml (milligrams per milliliter). In the case of orally administered substance

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

, the weight of chemical is labeled, athough the actual weight of the pill/capsule may be much higher, because of the use of filler substances. This means

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

that a small pill may be much more potent than a large pill, so don't judge a pill based on its size, but the actual amount of substance for which it is

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

labeled as.

mcg = microgram = 1/1000 of a mg (milligram) There are one thousand micrograms in one milligram.

Conversion factors:
1000 mcg (microgra

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

) = 1 mg (milligram)
1000 mg (milligram) = 1 g (gram)
1000 g (gram) = 1 kg (kilogram)
1000 ml (milliliter) = 1 liter
1ml (water) = 1cc

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

(water)
1ml (oil) ~ 1cc (oil) (~ denotes approximately equal to)

Examples putting it all together

Say a user has some Drug XYX from two differ

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ent companies. One is 'XYX-300' from QV, and one from BM which is 'XYZ-100'. Both of these are XYZ DRUG, but they have different concentrations. What this

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

means is....

for the XYZ-300:
if you take 1 ml (one milliliter) of this solution, it will take up ~1cc (one cubic centimeter) of space in the syring

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

e. There will be 300mg (three hundred milligrams) of XYZ in this dosage.

for the XYZ-100:
if you take 1 ml (one milliliter) of this solution, it wil

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

l take up ~1cc (one cubic centimeter) of space in the syringe. There will be 100mg (one hundred milligrams) of XYZ in this dosage.

If you put the syringe

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

side by side, they appear the exact same, so what is the difference? the XYZ-300 has a concentration of 300mg/ml, while the XYZ-100 only has a concentrat

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ion of 100mg/ml. This means that the syringe with XYZ-300 has three times (3x) the amount of DRUG XYZ in the same exact volume as the syringe with XYZ-100

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Your staffing woes are due vastly in part to lack of strong management. From here forward, I'll use management and leadership, interchangeably. Management is not entirely relegated to a person. This comes as a surprise to you, does it not? Do not think this means you can layoff your Office Manager or Department Managers in the near future. You will need them, along with your team, to turn things around

Google AdSense is a great way for anyone with a web site to make money. Those who want to create sites often do so simply to tap into the money making possibilities AdSense offers. But, to really get the most of out this advertising program, web site owners need to follow a few AdSense tips.

An article about what medical malpractice is and what the common causes of it are.

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