Suggest - Health and Fitness

Diabetes sufferers are well aware of the various related health problems which can be caused by the illness. One problem w

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

hich often gets overlooked is the link between diabetes and periodontal disease. Periodontal disease is the general term f

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

or diseases of the mouth which affect the gums and the bones that hold the teeth. A high incidence of teeth and gum proble

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ms in diabetics has been directly linked to the disease and poor control of blood sugar levels.

Diabetes causes changes t

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

o the blood vessels and makes it difficult for the body to naturally remove waste from the body tissue and replace it with

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

nutrients. Additionally the higher sugar levels can promote the growth of bacteria which can lead to gum disease. Adding

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

to these problems caused by diabetes by having poor oral hygiene will soon cause gingivitis which is the first stage of pe

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

riodontal disease. Diabetics who smoke are also much more likely to suffer from problems related to gum disease. It has b

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

een noted however that people with their diabetes under control will often have perfectly normal gums and teeth.

The seco

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

nd stage of periodontal disease that the diabetic usually suffers from is periodontitis, this is an infection of the bone

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

around the teeth which causes the bone to decay. If untreated the periodontitis will lead to loose teeth and eventually th

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

e loss of the teeth. In its initial mild form periodontitis is easily treated but if left untreated is can soon become ad

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

vanced periodontitis which results in the loss of large areas of bone and teeth. Although periodontal disease can be very

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

serious the diabetic can help to control it or indeed completely prevent it with care and a good oral hygiene routine.

T

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

he key to preventing periodontal disease is to adopt a rigorous oral hygiene routine. Regular brushing after each meal and

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

before bed time can help prevent the formation of plaque which can lead to gingivitis. The teeth should be flossed on a r

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

egular basis, many people don’t floss correctly so it is imperative that you get your dentist to show you how it should be

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

done. If the onset of periodontitis has already begun then the first step to curing it is to have all the plaque removed

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

. In the early stages this is often enough to halt the disease and repair the damage. With proper diabetic control, a good

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

oral hygiene routine and regular checkups diabetes and periodontal disease need not be a serious problem for the diabetic

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

HTTP = HTML link (for blogs, profiles,phorums):
<a href="http://www.suggest.org.ua/article/241550/suggest-The-Link-Between-Diabetes-and-Periodontal-Disease.html">The Link Between Diabetes and Periodontal Disease</a>

BB link (for phorums):
[url=http://www.suggest.org.ua/article/241550/suggest-The-Link-Between-Diabetes-and-Periodontal-Disease.html]The Link Between Diabetes and Periodontal Disease[/url]

Feel like gardening today? Don't know where to start? No problem you can find all the gardening tips you want from vast variety of gardening ebooks available on the web. You can learn how to start a garden, how to care for plants, which plants are easier to care for, when to plant and much, much more. Starting out you can find literature to help you choose whether you want a flower garden, or the one that grows vegetables.

Many wealthy people we read about seem to have a certain skill for creating large amounts of money. Many in this group of wealth builders follow a few simple rules in their wealth development strategy, and I have listed some here.

Tags

Links

Suggest - The Link Between Diabetes and Periodontal Disease

Related Articles: