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Anyone who has been at the local YMCA or health club will know what I mean when I say the times have changed. It used to be you would find treadmills everywhere, but now they

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

have been replaced with the hottest item in fitness today….elliptical trainers. Don't get me wrong, treadmills are still popular and continue to outsell elliptical machines

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

n total numbers, but the sale of these elliptical trainers are growing much quicker.

Why? What makes these fitness machines so popular? There are several reasons, but two m

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

in factors come to mind:

• Low impact workout on your body

• You get an upper and lower body workout

Why is a low impact workout important?

Think about this. Almost all t

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ypes of exercises create some form of impact on your body. Look at walking for example. Every step you take produces force on your feet, ankles, knees and even your lower ba

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

k. It may not seem like that sounds like a big deal, but over the years this can create stress and even injuries on those parts of your body. If you are a runner this is gre

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

tly multiplied due to the fact that running can produce up to 3 times your body weight on all those joints.

Using an elliptical fitness trainer safely reduces the impact on t

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

hese bones and joints. Because of its elliptical motion, you feel like you are normally walking, or running, without the potentially damaging impact. Another good thing is t

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

at this is a weight bearing exercise and will help tone and strengthen your muscles.

Take a moment to stand at the side of any elliptical trainer and take a look at it. You

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

an see that the motion looks like a flat circular movement. The lower quality elliptical machines have more of a bouncy and circular motion to them. No matter what though, t

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ese fitness trainers give your body a good workout, without the added impact. Folks of all ages are using them and they are quickly becoming the choice for baby boomers.

Why

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

is and Upper and Lower Body Workout Important?

Never before have you been able to get a complete upper and lower body workout from the same fitness machine, at the same time

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

That's what makes the elliptical so unique. You can get a good workout using your quadriceps, hamstrings, back, chest, triceps and biceps. Not one other machine can do all

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

that at the same time. You are also able to optimize your energy using an elliptical. This means that will take less time to reach more results. You will be able to burn mo

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

re calories and increase your cardio capacity. Many of the elliptical machines will also go backwards. This gives even more of added benefit to your muscles during a workout

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

The experts all agree that that by exercising more of your muscle groups you burn more calories, build more muscle and improve your endurance. An elliptical provides a way

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

f exercising with a reduced rate of exertion. You're still getting a great fitness workout, but it's not as strenuous. It's a true win-win situation.

By having an elliptica

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

l providing both an upper and lower body workout combined with low impact exercise, its no wonder these machines have become so popular. One other important point of interest

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

is the fact that compared to treadmills, elliptical trainers require very little maintenance. There are fewer moving parts and no motor.

I would encourage those who haven't

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

aken the opportunity to use an elliptical trainer to go to your local fitness club and do so. I believe that once you do you and your body will enjoy the experience immensely

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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