Suggest - Health and Fitness

TOO FAT

TOO THIN

You’ve got the same problem!

For over 90% of people who have a weight problem, the problem can be directly related to the amount of food you consume. It is no secret that the human body likes

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

to store excess food intake as fat. So if you eat more than you need you are going to pile on those kilos of fat. Conversely if you eat less than you need then your body will not build fat reserves and in extreme

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

cases of too little food intake the body will begin to use up the muscle mass to maintain it’s primary functions.

So be under no illusions that YOU ARE WHAT YOU EAT.

Well, what can we do about it?

TOO THIN

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

It can be as difficult to gain weight, as it is to lose it. Most people do not recognize this as being a problem. A lot of people will be envious of your dilemma. Well eat more. It doesn’t need to be difficult.

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

Just add a small amount to each meal, don’t try to ‘Super Size Me’ if that is not what you are capable of eating in one sitting. Try to squeeze in an extra snack in the morning and afternoon.

Don’t think this me

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ns stuffing junk down your throat all day long, candy bars, sweet stuff. No, make it good food, some protein and carbohydrates. Try some new foods and flavors. Try different styles of cooking. In fact start to ma

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

e more of your own stuff. As your interest in creating new and delicious meals increases so will your appreciation of food.

Take a class in cooking and entertaining, try to make food something you are interested

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

in. Let’s face it we all need food to survive so enjoy it.

TO FAT
Eat less and engage in more physical activity. Remember the body stores the food we do not need as fat. Eat too much and pile on the fat cel

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

s. More people suffer from being overweight or from easily gaining weight so this is perceived as being a more difficult thing to control. It isn’t

What you do need is to exercise some self-discipline. In this i

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

stance you need to cut out the snacks and reduce the size of your meals. You may need to be more drastic than thin people trying to gain weight. You already enjoy eating, so much in fact that you already eat too

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

uch. There is no magic bullet or pill. Try using a smaller plate at mealtime and don’t pile it high. Try to eat more protein that carbohydrate. Protein makes you feel fuller for longer. A thick nutritious soup w

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ll keep you feeling fuller for longer than a standard meal of the same calorific value.

Very important for this group is the need to increase your level of physical activity. Provided your food intake is now at

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

level slightly below what you need to stay where you are, the increase in physical activity will increase your rate of weight loss. Your body will begin to use up those fat reserves it has been storing.

METABOL

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

SM
What about it? Research has shown that metabolism doesn’t vary that much. True there are differences but it is not a reason or excuse for either TOO THIN or TOO FAT. So forget about it and put into place

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

n action plan to get you where you want to be.

WHAT YOU NEED TO DO
Find out what your weight should be by researching a few freely available information sheets on weight / height averages for male and femal

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

. The Metropolitan Life Insurance Company introduced a table in 1943 and revised it in 1993, it puts the details in an easy to read format and explains some basic details. You can find this on the ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

w" href="http://www.halls.md/ideal-weight/met.htm">Internet along with hundreds of others.

Work out your daily intake requirement. Again lots of resources are available on the Internet. To gain weight, incre

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

se your daily intake by 500 calories. To lose weight, cut your daily intake by 500 calories. Medicdirect has a great

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

esource for helping you work out your ideal requirements.

Next you need to design your plan around what you know now i.e. what you have found out about what your ideal weight should be.

TAKE ACTION
Develop

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

your plan and stick to it. Tell people about what you are doing, that often gives you the reason you need to stick with your plan. Give yourself as many reasons as possible to push yourself to succeed.

Go for it

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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