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Why is it so much easier to have a negative attitude than a positive one? What's inside you that just naturally pulls you to the negative side of things?

You read the books, you attend the seminars, you buy the tapes.....and

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

things seem to go well for awhile. You feel better, your outlook is better, and you're hopeful. That is.....until something happens that sends you reeling all over again.

It doesn't even have to be a major, catastrophic ev

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ent to send you back to the land of negative thinking. It can be something as simple as someone cutting you off in traffic or pushing ahead of you in the grocery checkout line. What gives those seemingly simple occurences of

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

every day life so much power to literally throw you into a tizzy all over again?

Negative attitudes come from negative thoughts that come from reactions to negative behavior....and around the cycle goes. And you must know t

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

hat none of this negative stuff is coming from God. There is nothing negative about the way He thinks or acts.

This never ending cycle continues because the source is never addressed. You "try hard" to be positive, attempti

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ng to over-ride how you truly feel. It's work pretending to be positive when inside you know all too well that it won't take long and one of those annoying life issues is going to creep up and dump all over your positive atti

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

tude.

So how do you put a stop to all this nonsense? How do you get to a place where your positive attitude is what's natural for you and not the other way around?

I wish I could give you a magic formula that, when applied

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

correctly, would erase your negative attitude in 3 days. Yup, can't you just see the infomercial on a product like that? For just $19.95 you can have all your dreams come true. What a bargain! People would be lining up for

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

this one.

But alas....the real world isn't quite so simple. But the good news is that there are some things you can do to help you transition from the land of negativity to a much more positive place.

First, focus o

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

n what you're thinking about. Remember when I said you seem stuck because you've never addressed the source of all of this? All your negative actions are coming from your negative thoughts. Your body goes right along wi

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

th whatever your mind is telling it.

It is possible to control your thoughts, regardless of what you've been led to believe. As soon as a negative thought comes into your mind, purposefully make it a point to replace it with

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

a positive one. At first, this may take some work, because chances are, you will probably have alot more negative thoughts in your head than positive ones. But eventually, that ratio will reverse itself.

Second, sto

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

p letting other people's negative attitudes influence yours. This may mean you need to stop hanging around with people who do nothing but spout negative stuff. You can't afford it when your goal is to become more positiv

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

e. The negative people in your life aren't going to like it when you will no longer participate. Just remember that birds of a feather really do flock together.

Third, make a list of all the areas in your life that y

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ou want to change. List all your negative attitudes too. If you can't really think of things to put on your list, just ask your family. I'll bet they'll help you make it a REALLY LONG list.

Fourth, take the time

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

to write strong, life-giving, positive affirmative statements. Make a commitment to read those statements out loud every day. Enjoy how great they make you feel. Know in your heart that you're making progress, even if

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

you can't see it just yet. Just keep affirming the positive.

Lastly, take the time to pray about this. You can't change by yourself. But you can spend time with the One who can help. You do what you can, and yo

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

u let God do the rest. It really IS that simple.

This process will change how you think and that's the real key to changing how you act. Remember.....your body will follow right behind your thoughts. There is no way t

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

o separate the two, so you might as well "program in" what you want instead of randomly leaving it to chance.

Just know that God's version of right attitudes don't contain anything negative. And if you want God's best for yo

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ur life, it starts with right thoughts.....His thoughts to be exact.

For more help go to Attitude Really Does Make a Difference

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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