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Our ordinary mind cannot stay still for longer than a few moments without grasping after distractions. It is fragmented into so many

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

different aspects that we don't know who we really are, or what aspects of ourselves we should identify with or believe in. So many c

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ontradictory voices, dictates and feelings fight for control over our lives that we find ourselves scattered in all directions.

So w

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

en anything has to be done of a sustained nature the first thing one does is to draw back all of the dispersed consciousness and conc

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

entrate on the single idea or subject. It is then that the individual is hopefully able to eliminate all of the superfluous thoughts

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

and apply concentrated effort to the task at hand. But if we are finding it difficult to concentrate are there any techniques that ca

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

help? Certainly one of the best is meditation.

The mind is always in activity, but when we meditate we do not observe fully what th

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e mind is doing, we keep our focus of concentrated awareness at a distance from the mind's endless activities. At this distance we in

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

tentionally avoid focusing on the thoughts, allowing them to pass before us, unnoticed. Time and time again during our meditations th

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ughts pass before us, but we steadily remain in the focused moment, ignoring the passing distractions.

Our ability to stand back fro

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

m the unwanted thoughts keeps us in the gap of meditative awareness. Free for only as long as we quietly allow the thoughts to pass b

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

y, the moment we attach our concentration, even for a fleeting second to a thought we loose the silence of the moment and are caught

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

y the contradictory thoughts of the mind. Such success does not come easily at first, but with patience and over time the mechanical

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

whirl of the mind begins to die away leaving you with the silence and quietude of the spiritual heart.

Then in the meditation our co

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ncentration is no longer scattered by contradictory voices or feelings of the physical mind, being replaced instead with the positive

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

awareness of the heart's poise and wisdom. Here a positive attitude quickly develops within an individual giving them the capacity an

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

d conviction to make clear, focused and uncluttered decisions.

Sri Chinmoy the meditation teacher says, (1) "Each thought has power

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

of its own. Positive thought has a power and negative thought also has a power. With positive power we build; with negative power we

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

reak. Each positive thought is creation and each negative thought is destruction...we can get rid of negative thoughts with our heart

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

's will power. During our meditation, slowly and steadily we develop will power".

Ref: (1) From Sri Chinmoy's book - The Wings of Jo

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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